Amino Acids, Peptides and Proteins: Volume 38 by Etelka Farkas, Maxim Ryadnov, Max Cryle, K. Kover, John

By Etelka Farkas, Maxim Ryadnov, Max Cryle, K. Kover, John Wade, Hisakazu Mihara, A. Henrion, Gabor Mezo

Amino Acids, Peptides and Proteins includes a finished evaluation of important advancements at this biology/chemistry interface. every one quantity of this professional Periodical record opens with an outline of amino acids and their purposes. in response to the preceeding volumes within the sequence, this quantity provides contributions from around the globe addressing the new issues within the box. Disulfide-containing peptides and proteins are investigated by way of NMR, and mass spectrometry is used to figure out inter-peptide far-off constraints. additional chapters evaluation the newest literature on antimicrbial peptides, variations via Cytochrome P450 and the relaxin-family neuropeptides. Self-assembly and the moleculatr popularity of designed peptides also are mentioned, and the newest in peptide and protein-based prescription drugs are reviewed. quantity editor Max Ryadnov additionally contributes a bankruptcy on biofunctional peptide layout. because the released literature within the box keeps to develop, researchers in academia and will locate this finished evaluation of the present study and suggestion a vital, first-stop reference.

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44 E. Conti, T. Stachelhaus, M. A. Marahiel and P. , 1997, 16, 4174–4183. 45 T. A. Keating, C. G. Marshall, C. T. Walsh and A. E. Keating, Nat. Struct. , 2002, 9, 522–526. 46 S. D. Bruner, T. Weber, R. M. Kohli, D. Schwarzer, M. A. Marahiel, C. T. Walsh and M. T. Stubbs, Structure, 2002, 10, 301–310. 47 D. Bischoff, S. Pelzer, B. Bister, G. J. Nicholson, S. Stockert, M. Schirle, W. Wohlleben, G. Jung and R. D. Su¨ssmuth, Angew. Chem. Int. , 2001, 40, 4688–4691. -L. Li, F. Huang, S. F. Haydock, T.

A. Townsend, J. , 2005, 187, 739–746. 92 M. Gondry, L. Sauguet, P. Belin, R. Thai, R. Amouroux, C. Tellier, K. Tuphile, M. Jacquet, S. Braud, M. Courc¸on, C. Masson, S. Dubois, S. Lautru, A. Lecoq, S. Hashimoto, R. -L. Pernodet, Nat. Chem. , 2009, 5, 414–420. 34 | Amino Acids, Pept. Proteins, 2013, 38, 1–36 . 1039/9781849737081-00001 View Online 93 S. M. Barry, J. A. Kers, E. G. Johnson, L. Song, P. R. Aston, B. Patel, S. B. Krasnoff, B. R. Crane, D. M. Gibson, R. Loria and G. L. Challis, Nat. Chem.

Biol. 1021/cb400555e. 36 | Amino Acids, Pept. Proteins, 2013, 38, 1–36 NMR investigation of disulfide containing peptides and proteins Katalin E. Ko¨ve´r*a and Gyula Battab 01/12/2013 14:44:18. 1039/9781849737081-00037 1 Introduction We give a short overview of the literature covering a period from 2011 to 2013 concentrating rather to peptides and small proteins and some recent advances in solution NMR technology devoted to disclosing the structure of disulfide peptides and proteins. Disulfide peptides and proteins are not only interesting for their own structural curiosities and biological significance.

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