Depressive Illness: Prediction of Course and Outcome by J. Angst (auth.), Professor Tómas Helgason, Professor Robert

By J. Angst (auth.), Professor Tómas Helgason, Professor Robert J. Daly (eds.)

The staff of ecu scientific study Councils (EMRC) used to be shaped in 1971 and have become a status Committee of the ecu technology origin (ESF) in 1975. EMRC is an organization of clinical study councils or identical businesses in Western Europe. The nationwide Institutes of healthiness, the Israel Academy of Sciences and the ecu place of work of who're linked to EMRC and take an lively half in EMRC actions. the most goals of EMRC are to switch info at the learn rules pursued by way of its member corporations and to begin and stimulate overseas cooperation in biomedical examine. considering that biomedical examine is extremely overseas in itself, EMRC concentrates its actions on furthering foreign collaboration in these fields the place it could play an important position as a supplement to current channels. psychological disorder study has been judged via EMRC to meet those standards. After a survey of the actions of the member agencies in psychological disease learn, EMRC determined in 1978 to establish a research workforce to seem for parts inside of this box to which EMRC may possibly give a contribution. as a result of paintings of the examine workforce, 4 paintings­ retailers were prepared to outline current wisdom in a few particular components and to delineate study wishes. the current quantity includes the lawsuits of the fourth workshop, held in 1985 and working with the path and final result of depressive disease. EMRC hopes that this quantity will stimulate intensified examine and study cooperation on psychological illnesses.

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In a 3-year prospective follow-up study (Lonnqvist et al. 5 times in manic depressives. The risk for suicide was about 30 times that of a normal population. In the prospective Lundby study by Hagnell et al. (1981) the suicide rate of male depressives was 13 times higher than expected. The suicides show a small peak in spring (Taschev and Roglev 1973). Patients who committed suicide had usually communicated their intent during their lifetime (Fowler et al. 1979). An interesting question is whether there is any difference between suicide rates in unipolar depression and bipolar disorder.

Pilcz (1901) discussed the effect ofhospitalization inducing changes of the temperament in the sense of becoming irritable, unpredictable, indolent, and egocentric. Meyer (1874) described a lowered reactivity as a residual phenomenon. Von Hosslin (1909) studied late-onset manic-depressive psychoses at the beginning of this century, and extensively described patients being in the hospital with a loss of interest, loss of reactivity to visits of relatives, and egocentric, apathetic, and dumb behavior.

J Affective Disord 8:207-213 Kerr TA, Schapira K, Roth M (1969) The relationship between premature death and affective disorders. Br J Psychiatry 115:1277-1282 Kerr TA, Roth M, Schapira K, Gurney C (1972) The assessment and prediction of outcome in affective disorders. Br J Psychiatry 121:167-174 Kielholz P (1959) Klinik, Differentialdiagnostik und Therapie der depressiven Zustandsbilder. 2) Kimura S, Ohya D, Koh T, Iwamura H (1984) Course and prognosis of endogenous-phasic psychoses in adolescence.

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